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Literature summary extracted from

  • Shibuya-Saruta, H.; Kasahara, Y.; Hashimoto, Y.
    Human serum dipeptidyl peptidase IV (DPPIV) and its unique properties (1996), J. Clin. Lab. Anal., 10, 435-440.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.14.5 Gln activates Homo sapiens
3.4.14.5 Glu activates Homo sapiens
3.4.14.5 Gly activates Homo sapiens
3.4.14.5 Gly-X dipeptides enhance activity Homo sapiens
3.4.14.5 glycine methylesters activates Homo sapiens
3.4.14.5 Ser activates Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.14.5 Cd2+ CdCl2 Homo sapiens
3.4.14.5 Diprotin A
-
 Homo sapiens
3.4.14.5 Hg2+ HgCl2 Homo sapiens
3.4.14.5 Leu
-
 Homo sapiens
3.4.14.5 Lys
-
 Homo sapiens
3.4.14.5 Met
-
 Homo sapiens
3.4.14.5 PCMB
-
 Homo sapiens
3.4.14.5 SrCl2
-
 Homo sapiens
3.4.14.5 Zn2+ ZnCl2 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.14.5 0.17
-
 Gly-Pro-3,5-dibromo-4-hydroxyanilide
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.14.5 100000
-
 2 * 100000, SDS-PAGE Homo sapiens
3.4.14.5 230000 250000 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.14.5 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.14.5
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.14.5 serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.14.5 Gly-azetidine-2-carboxyl-3,5-dibromo-4-hydroxyanilide + H2O
-
 Homo sapiens Gly-azetidine + 3,5-dibromo-4-hydroxyaniline
-
 ?
3.4.14.5 Gly-L-hydroxyproline-3,5-dibromo-4-hydroxyanilide + H2O
-
 Homo sapiens Gly-L-hydroxyproline + 3,5-dibromo-4-hydroxyaniline
-
 ?
3.4.14.5 Gly-Pro-3,5-dibromo-4-hydroxyanilide + H2O
-
 Homo sapiens Gly-Pro + 3,5-dibromo-4-hydroxyaniline
-
 ?
3.4.14.5 Gly-Pro-4-nitroanilide + H2O
-
 Homo sapiens Gly-Pro + 4-nitroaniline
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.14.5 dimer 2 * 100000, SDS-PAGE Homo sapiens

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.14.5 810
-
 Gly-Pro-3,5-dibromo-4-hydroxyanilide
-
 Homo sapiens