Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Nordwig, A.; Mayer, H.
    The cleavage of prolyl peptides by kidney peptidases. Detection of a new peptidase capable of removing N-terminal proline (1973), Hoppe-Seyler's Z. Physiol. Chem., 354, 380-383.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.5 p-chloromercuribenzoate
-
 Sus scrofa
3.4.13.18 p-chloromercuribenzoate
-
 Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.5 300000
-
 gel filtration Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.11.5 additional information Sus scrofa discussion of biological significance ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.5 Sus scrofa
-
-
-
3.4.13.18 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.5 partial Sus scrofa
3.4.13.18 partial Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.5 kidney cortex Sus scrofa
-
3.4.13.18 kidney
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.11.5 780
-
 Pro-Leu-NH2 Sus scrofa
3.4.13.18 additional information
-
-
 Sus scrofa

Storage Stability

EC Number Storage Stability Organism
3.4.11.5 -20°C or 4°C Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.5 L-prolyl-peptide + H2O influence of amino acid adjacent to N-terminal L-Pro on rate of hydrolysis Sus scrofa L-proline + peptide
-
 ?
3.4.11.5 additional information discussion of biological significance Sus scrofa ?
-
 ?
3.4.11.5 poly-(L-Pro) + H2O no hydrolysis Sus scrofa proline
-
 ?
3.4.13.18 Pro-Gly + H2O
-
 Sus scrofa Pro + Gly
-
 ?
3.4.13.18 Pro-Leu + H2O
-
 Sus scrofa Pro + Leu
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.5 9 9.5
-
 Sus scrofa