BRENDA - Enzyme Database

A soluble 2,3-oxidosqualene sterol cyclase

Dean, P.D.G.; Ortiz de Montellano, P.R.; Bloch, K.; Corey, E.J.; J. Biol. Chem. 242, 3014-3015 (1967)

Data extracted from this reference:

General Stability
EC Number
General Stability
Organism
5.4.99.7
rapid loss of activity on freezing and thawing
Sus scrofa
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
5.4.99.7
2,2-dimethyl-3-[(3E,7E,11E,15E)-3,7,12,16,20-pentamethylhenicosa-3,7,11,15,19-pentaen-1-yl]aziridine
-
Sus scrofa
5.4.99.7
NEM
1 mM, 20% inhibition
Sus scrofa
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.4.99.7
microsome
-
Sus scrofa
-
-
Organism
EC Number
Organism
UniProt
Commentary
Textmining
5.4.99.7
Sus scrofa
-
hog
-
Purification (Commentary)
EC Number
Purification (Commentary)
Organism
5.4.99.7
-
Sus scrofa
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.4.99.7
liver
-
Sus scrofa
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
5.4.99.7
additional information
-
-
Sus scrofa
Storage Stability
EC Number
Storage Stability
Organism
5.4.99.7
0°C, stable
Sus scrofa
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
5.4.99.7
(S)-squalene-2,3-epoxide
-
3589
Sus scrofa
Lanosterol
-
3589
Sus scrofa
-
General Stability (protein specific)
EC Number
General Stability
Organism
5.4.99.7
rapid loss of activity on freezing and thawing
Sus scrofa
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
5.4.99.7
2,2-dimethyl-3-[(3E,7E,11E,15E)-3,7,12,16,20-pentamethylhenicosa-3,7,11,15,19-pentaen-1-yl]aziridine
-
Sus scrofa
5.4.99.7
NEM
1 mM, 20% inhibition
Sus scrofa
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.4.99.7
microsome
-
Sus scrofa
-
-
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
5.4.99.7
-
Sus scrofa
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.4.99.7
liver
-
Sus scrofa
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
5.4.99.7
additional information
-
-
Sus scrofa
Storage Stability (protein specific)
EC Number
Storage Stability
Organism
5.4.99.7
0°C, stable
Sus scrofa
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
5.4.99.7
(S)-squalene-2,3-epoxide
-
3589
Sus scrofa
Lanosterol
-
3589
Sus scrofa
-