Literature summary extracted from

Werner, R.G.; Thorpe, L.F.; Reuter, W.; Nierhaus, K.H.
Indolmycin inhibits prokaryotic tryptophanyl-tRNA ligase (1976), Eur. J. Biochem., 68, 1-3.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
6.1.1.2	indolmycin	specifically inhibits enzyme	Escherichia coli
6.1.1.2	indolmycin	liver enzyme is affected much less	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.1.1.2	Escherichia coli	-	-	-
6.1.1.2	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
6.1.1.2	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.1.1.2	ATP + L-tryptophan + tRNATrp	-	Escherichia coli	AMP + diphosphate + L-tryptophan-tRNATrp	-	?
6.1.1.2	ATP + L-tryptophan + tRNATrp	-	Rattus norvegicus	AMP + diphosphate + L-tryptophan-tRNATrp	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)