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Literature summary extracted from
- Immunochemical characterization of NADPH-cytochrome P-450 reductase from Jerusalem artichoke and other higher plants (1989), Biochem. J., 259, 847-853.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.6.2.4 | 3-Aminonicotinamide adenine dinucleotide phosphate | - |
Helianthus tuberosus |  |
| 1.6.2.4 | NADP+ | - |
Helianthus tuberosus | |
| 1.6.2.4 | NADP+ | - |
Locusta migratoria migratorioides | |
| 1.6.2.4 | NADP+ | - |
Sus scrofa | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.6.2.4 | microsome | - |
Rattus norvegicus | - |
- |
| 1.6.2.4 | microsome | - |
Sus scrofa | - |
- |
| 1.6.2.4 | microsome | - |
Saccharomyces cerevisiae | - |
- |
| 1.6.2.4 | microsome | - |
Embryophyta | - |
- |
| 1.6.2.4 | microsome | - |
Helianthus tuberosus | - |
- |
| 1.6.2.4 | microsome | - |
Locusta migratoria migratorioides | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.6.2.4 | additional information | - |
- |
Helianthus tuberosus |
| 1.6.2.4 | additional information | - |
a weak band at the level of the Jerusalem artichoke reductase | Saccharomyces cerevisiae |
| 1.6.2.4 | 82000 | 85000 | - |
Saccharomyces cerevisiae |
| 1.6.2.4 | 82000 | 85000 | SDS-PAGE followed by Western blotting | Helianthus tuberosus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.6.2.4 | NADPH + ferricytochrome P450 | Sus scrofa | - |
ferrocytochrome P450 + NADP+ | - |
? | |
| 1.6.2.4 | NADPH + ferricytochrome P450 | Embryophyta | - |
ferrocytochrome P450 + NADP+ | - |
? | |
| 1.6.2.4 | NADPH + ferricytochrome P450 | Helianthus tuberosus | - |
ferrocytochrome P450 + NADP+ | - |
? | |
| 1.6.2.4 | NADPH + ferricytochrome P450 | Locusta migratoria migratorioides | - |
ferrocytochrome P450 + NADP+ | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.6.2.4 | Embryophyta | - |
e.g. maize, potato, avocado, bramble, tulip, leek, Vicia faba, sunflower, bramble, Gingko biloba | - |
| 1.6.2.4 | Helianthus tuberosus | - |
L. var. Blanc commun., Jerusalem artichoke | - |
| 1.6.2.4 | Locusta migratoria migratorioides | - |
- |
- |
| 1.6.2.4 | Rattus norvegicus | - |
- |
- |
| 1.6.2.4 | Saccharomyces cerevisiae | - |
- |
- |
| 1.6.2.4 | Sus scrofa | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.6.2.4 | anion exchange chromatography and affinity chromatography | Helianthus tuberosus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.6.2.4 | bulb | - |
Embryophyta | - |
| 1.6.2.4 | liver | - |
Rattus norvegicus | - |
| 1.6.2.4 | liver | - |
Sus scrofa | - |
| 1.6.2.4 | mesocarp | - |
Embryophyta | - |
| 1.6.2.4 | midgut | - |
Locusta migratoria migratorioides | - |
| 1.6.2.4 | seedling | Vicia faba, leek, sunflower | Embryophyta | - |
| 1.6.2.4 | tuber | - |
Helianthus tuberosus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.6.2.4 | 2 ferricytochrome c + NADPH | - |
Locusta migratoria migratorioides | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
| 1.6.2.4 | 2 ferricytochrome c + NADPH | additional electron acceptor: ferricyanide | Rattus norvegicus | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
| 1.6.2.4 | 2 ferricytochrome c + NADPH | additional electron acceptor: ferricyanide | Saccharomyces cerevisiae | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
| 1.6.2.4 | 2 ferricytochrome c + NADPH | additional electron acceptor: ferricyanide | Helianthus tuberosus | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
| 1.6.2.4 | 2 ferricytochrome c + NADPH | additional electron acceptor: 2,6-dichlorophenolindophenol | Rattus norvegicus | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
| 1.6.2.4 | 2 ferricytochrome c + NADPH | additional electron acceptor: 2,6-dichlorophenolindophenol | Sus scrofa | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
| 1.6.2.4 | 2 ferricytochrome c + NADPH | additional electron acceptor: 2,6-dichlorophenolindophenol | Saccharomyces cerevisiae | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
| 1.6.2.4 | 2 ferricytochrome c + NADPH | additional electron acceptor: 2,6-dichlorophenolindophenol | Helianthus tuberosus | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
| 1.6.2.4 | NADPH + ferricytochrome P450 | - |
Sus scrofa | ferrocytochrome P450 + NADP+ | - |
? | |
| 1.6.2.4 | NADPH + ferricytochrome P450 | - |
Embryophyta | ferrocytochrome P450 + NADP+ | - |
? | |
| 1.6.2.4 | NADPH + ferricytochrome P450 | - |
Helianthus tuberosus | ferrocytochrome P450 + NADP+ | - |
? | |
| 1.6.2.4 | NADPH + ferricytochrome P450 | - |
Locusta migratoria migratorioides | ferrocytochrome P450 + NADP+ | - |
? | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.6.2.4 | NADPH | - |
Rattus norvegicus | |
| 1.6.2.4 | NADPH | - |
Sus scrofa | |
| 1.6.2.4 | NADPH | - |
Saccharomyces cerevisiae | |
| 1.6.2.4 | NADPH | - |
Embryophyta | |
| 1.6.2.4 | NADPH | - |
Helianthus tuberosus | |
| 1.6.2.4 | NADPH | - |
Locusta migratoria migratorioides | |
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