Literature summary extracted from

Ijau, R.K.; Herndon, C.A.; Hawes, J.W.
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus infuenzae (2000), J. Biol. Chem., 275, 38780-38786.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.1.1.60	overexpression in Escherichia coli	Haemophilus influenzae
1.1.1.60	overexpression in Escherichia coli	Escherichia coli

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.1.1.60	0.048	-	(R)-beta-hydroxybutyrate	-	Haemophilus influenzae
1.1.1.60	0.06	-	D-threonine	-	Haemophilus influenzae
1.1.1.60	0.28	-	D-glycerate	-	Escherichia coli
1.1.1.60	3.7	-	D-glycerate	-	Haemophilus influenzae
1.1.1.60	4.2	-	L-Glycerate	-	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.60	Escherichia coli	-	-	-
1.1.1.60	Haemophilus influenzae	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.1.1.60	of recombinant protein	Haemophilus influenzae
1.1.1.60	of recombinant protein	Escherichia coli

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.60	(R)-beta-hydroxybutyrate + NAD+	-	Haemophilus influenzae	?	-	?
1.1.1.60	(R)-glycerate + NAD(P)+	-	Haemophilus influenzae	tartronate semialdehyde + NAD(P)H	-	r
1.1.1.60	(R)-glycerate + NAD(P)+	-	Escherichia coli	tartronate semialdehyde + NAD(P)H	-	r
1.1.1.60	D-threonine + NAD+	-	Haemophilus influenzae	?	-	?
1.1.1.60	L-glycerate + NAD+	-	Escherichia coli	?	-	r
1.1.1.60	tartronate semialdehyde + NAD(P)H	-	Haemophilus influenzae	(R)-glycerate + NAD(P)+	-	r
1.1.1.60	tartronate semialdehyde + NAD(P)H	-	Escherichia coli	(R)-glycerate + NAD(P)+	-	r

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.1.60	beta-hydroxyacid dehydrogenase	-	Haemophilus influenzae
1.1.1.60	beta-hydroxyacid dehydrogenase	-	Escherichia coli

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Release 2023.1 (January 2023)