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Literature summary extracted from

  • Federiuk, C.S.; Bayer, R.; Shafer, J.A.
    Characterization of the catalytic pathway for D-serine dehydratase (1983), J. Biol. Chem., 258, 5379-5385.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.3.1.18 0.083
-
 D-Thr pH 5.7, 25°C Escherichia coli
4.3.1.18 0.086
-
 D-Ser pH 5.7, 25°C Escherichia coli
4.3.1.18 0.24
-
 D-Ser pH 7.8, 5°C Escherichia coli
4.3.1.18 0.35
-
 D-Ser pH 7.8, 25°C Escherichia coli
4.3.1.18 0.68
-
 D-Thr pH 7.8, 25°C Escherichia coli
4.3.1.18 1.1
-
 D-allothreonine pH 5.7, 25°C Escherichia coli
4.3.1.18 1.68
-
 D-Ser pH 8.9, 25°C Escherichia coli
4.3.1.18 2.4
-
 D-allothreonine pH 7.8, 25°C Escherichia coli
4.3.1.18 4
-
 L-Ser pH 7.8, 25°C Escherichia coli
4.3.1.18 4.9
-
 D-allothreonine pH 8.9, 25°C Escherichia coli
4.3.1.18 11
-
 L-Ser pH 5.8, 25°C Escherichia coli
4.3.1.18 12.3
-
 L-Ser pH 8.9, 25°C Escherichia coli
4.3.1.18 16
-
 D-Thr pH 8.9, 25°C Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
4.3.1.18 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.1.18 D-Allothreonine
-
 Escherichia coli ?
-
 ?
4.3.1.18 D-serine
-
 Escherichia coli pyruvate + NH3
-
 ?
4.3.1.18 D-threonine
-
 Escherichia coli 2-oxobutanoate + NH3
-
 ?
4.3.1.18 L-allothreonine
-
 Escherichia coli ?
-
 ?
4.3.1.18 L-serine very low activity Escherichia coli pyruvate + NH3
-
 ?
4.3.1.18 L-Thr
-
 Escherichia coli ?
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.3.1.18 0.112
-
 D-allothreonine pH 5.7, 25°C Escherichia coli
4.3.1.18 0.12
-
 L-Ser pH 5.8, 25°C Escherichia coli
4.3.1.18 0.14
-
 L-Ser pH 8.9, 25°C Escherichia coli
4.3.1.18 0.153
-
 L-Ser pH 7.8, 25°C Escherichia coli
4.3.1.18 0.92
-
 D-allothreonine pH 8.9, 25°C Escherichia coli
4.3.1.18 0.95
-
 D-Thr pH 5.8, 25°C Escherichia coli
4.3.1.18 1.8
-
 L-allothreonine pH 7.8, 25°C Escherichia coli
4.3.1.18 9.4
-
 D-Ser pH 5.7, 25°C Escherichia coli
4.3.1.18 17.2
-
 L-Thr pH 8.9, 25°C Escherichia coli
4.3.1.18 19.6
-
 L-Thr pH 7.8, 25°C Escherichia coli
4.3.1.18 30
-
 D-Ser pH 7.8, 5°C Escherichia coli
4.3.1.18 48
-
 D-Ser pH 8.9, 25°C Escherichia coli
4.3.1.18 118
-
 D-Ser pH 7.8, 25°C Escherichia coli