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Literature summary extracted from

  • Valenzuela, M.A; Ketttlun, A.M.; Sandoval, S.; Garcia, L.; Mancilla, M.; Neckelmann, G.; Chayet, L.; Alvarez, A.; Cuevas, F.; Collados, L.; Espinosa, V.; Traverso-Cori, A.; Bravo, I.; Acevedo, C.G.; Aranda, E.
    Comparison of the biochemical properties, regulation and function of ATP diphosphohydrolase from human placenta and rat kidney (1996), Braz. J. Med. Biol. Res., 29, 589-597.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.5 additional information no inhibition by ouabain Homo sapiens
3.6.1.5 additional information no inhibition by oligomycin; no inhibition by ouabain Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.6.1.5 membrane ectonucleotidase/ectoenzyme Homo sapiens 16020
-
3.6.1.5 membrane ectonucleotidase/ectoenzyme Rattus norvegicus 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.5 64000
-
 SDS-PAGE Homo sapiens
3.6.1.5 67000
-
 SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.5 ADP + H2O Homo sapiens
-
 AMP + phosphate
-
 ?
3.6.1.5 ADP + H2O Rattus norvegicus
-
 AMP + phosphate
-
 ?
3.6.1.5 ATP + 2 H2O Homo sapiens inhibition of platelet aggregation in the placenta AMP + 2 phosphate
-
 ?
3.6.1.5 ATP + 2 H2O Rattus norvegicus salvage of purine nucleobases in primary urine AMP + 2 phosphate
-
 ?
3.6.1.5 ATP + 2 H2O Homo sapiens regulation of extracellular ATP-level AMP + 2 phosphate
-
 ?
3.6.1.5 ATP + 2 H2O Rattus norvegicus regulation of extracellular ATP-level AMP + 2 phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.5 Homo sapiens
-
-
-
3.6.1.5 Rattus norvegicus
-
 rat
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.5 partially Homo sapiens
3.6.1.5 partially Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.5 kidney
-
 Homo sapiens
-
3.6.1.5 kidney
-
 Rattus norvegicus
-
3.6.1.5 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.5 ADP + H2O
-
 Homo sapiens AMP + phosphate
-
 ?
3.6.1.5 ADP + H2O
-
 Rattus norvegicus AMP + phosphate
-
 ?
3.6.1.5 ATP + 2 H2O
-
 Homo sapiens AMP + 2 phosphate
-
 ?
3.6.1.5 ATP + 2 H2O
-
 Rattus norvegicus AMP + 2 phosphate
-
 ?
3.6.1.5 ATP + 2 H2O inhibition of platelet aggregation in the placenta Homo sapiens AMP + 2 phosphate
-
 ?
3.6.1.5 ATP + 2 H2O salvage of purine nucleobases in primary urine Rattus norvegicus AMP + 2 phosphate
-
 ?
3.6.1.5 ATP + 2 H2O regulation of extracellular ATP-level Homo sapiens AMP + 2 phosphate
-
 ?
3.6.1.5 ATP + 2 H2O regulation of extracellular ATP-level Rattus norvegicus AMP + 2 phosphate
-
 ?
3.6.1.5 CDP + H2O
-
 Homo sapiens CMP + phosphate
-
 ?
3.6.1.5 CDP + H2O
-
 Rattus norvegicus CMP + phosphate
-
 ?
3.6.1.5 CTP + 2 H2O
-
 Homo sapiens CMP + 2 phosphate
-
 ?
3.6.1.5 CTP + 2 H2O
-
 Rattus norvegicus CMP + 2 phosphate
-
 ?
3.6.1.5 GDP + H2O
-
 Rattus norvegicus GMP + phosphate
-
 ?
3.6.1.5 GDP + H2O best substrate Homo sapiens GMP + phosphate
-
 ?
3.6.1.5 GTP + 2 H2O
-
 Homo sapiens GMP + 2 phosphate
-
 ?
3.6.1.5 GTP + 2 H2O best substrate Rattus norvegicus GMP + 2 phosphate
-
 ?
3.6.1.5 additional information neglible hydrolysis of AMP Homo sapiens ?
-
 ?
3.6.1.5 additional information neglible hydrolysis of AMP Rattus norvegicus ?
-
 ?
3.6.1.5 TTP + 2 H2O
-
 Homo sapiens TMP + 2 phosphate
-
 ?
3.6.1.5 TTP + 2 H2O
-
 Rattus norvegicus TMP + 2 phosphate
-
 ?
3.6.1.5 UDP + H2O
-
 Homo sapiens UMP + phosphate
-
 ?
3.6.1.5 UDP + H2O
-
 Rattus norvegicus UMP + phosphate
-
 ?
3.6.1.5 UTP + 2 H2O
-
 Homo sapiens UMP + 2 phosphate
-
 ?
3.6.1.5 UTP + 2 H2O
-
 Rattus norvegicus UMP + 2 phosphate
-
 ?