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Literature summary extracted from

  • Ota, K.; Hammock, B.D.
    Cytosolic and microsomal epoxide hydrolases: differential properties in mammalian liver (1980), Science, 207, 1479-1481.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.3.2.9 microsome
-
 Cavia porcellus
-
-
3.3.2.9 microsome
-
 Mus musculus
-
-
3.3.2.9 microsome
-
 Rattus norvegicus
-
-
3.3.2.10 cytosol
-
 Cavia porcellus 5829
-
3.3.2.10 cytosol
-
 Mus musculus 5829
-
3.3.2.10 cytosol
-
 Rattus norvegicus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.9 Cavia porcellus
-
-
-
3.3.2.9 Mus musculus
-
-
-
3.3.2.9 Rattus norvegicus
-
-
-
3.3.2.10 Cavia porcellus
-
-
-
3.3.2.10 Mus musculus
-
-
-
3.3.2.10 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.3.2.9 liver
-
 Cavia porcellus
-
3.3.2.9 liver
-
 Mus musculus
-
3.3.2.9 liver
-
 Rattus norvegicus
-
3.3.2.10 liver
-
 Cavia porcellus
-
3.3.2.10 liver
-
 Mus musculus
-
3.3.2.10 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.3.2.9 0.000085
-
 liver microsomes, substrate styrene oxide Mus musculus
3.3.2.9 0.000124
-
 liver microsomes, substrate styrene oxide Rattus norvegicus
3.3.2.9 0.00019
-
 liver microsomes, substrate allylbenzene oxide Mus musculus
3.3.2.9 0.00035
-
 liver microsomes, substrate allylbenzene oxide Rattus norvegicus
3.3.2.9 0.00043
-
 liver microsomes, substrate styrene oxide Cavia porcellus
3.3.2.9 0.0036
-
 liver microsomes, substrate allylbenzene oxide Cavia porcellus
3.3.2.10 0.00017
-
 liver cytosol, substrate trans-beta-methyl-styrene oxide Rattus norvegicus
3.3.2.10 0.00049
-
 liver cytosol, substrate trans-beta-methyl-styrene oxide Cavia porcellus
3.3.2.10 0.00157
-
 liver cytosol, substrate allylbenzene oxide Rattus norvegicus
3.3.2.10 0.00189
-
 liver cytosol, substrate trans-bety-methyl-styrene oxide Mus musculus
3.3.2.10 0.00264
-
 liver cytosol, substrate allylbenzene oxide Cavia porcellus
3.3.2.10 0.007
-
 liver cytosol, substrate allylbenzene oxide Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.9 allylbenzene + H2O
-
 Cavia porcellus 3-phenylpropane-1,2-diol
-
 ?
3.3.2.9 allylbenzene + H2O
-
 Mus musculus 3-phenylpropane-1,2-diol
-
 ?
3.3.2.9 allylbenzene + H2O
-
 Rattus norvegicus 3-phenylpropane-1,2-diol
-
 ?
3.3.2.9 styrene oxide + H2O
-
 Cavia porcellus 1-phenylethane-1,2-diol
-
 ?
3.3.2.9 styrene oxide + H2O
-
 Mus musculus 1-phenylethane-1,2-diol
-
 ?
3.3.2.9 styrene oxide + H2O
-
 Rattus norvegicus 1-phenylethane-1,2-diol
-
 ?
3.3.2.10 allylbenzene + H2O
-
 Cavia porcellus ?
-
 ?
3.3.2.10 allylbenzene + H2O
-
 Mus musculus ?
-
 ?
3.3.2.10 allylbenzene + H2O
-
 Rattus norvegicus ?
-
 ?
3.3.2.10 trans-beta-methyl-styrene oxide + H2O
-
 Cavia porcellus ?
-
 ?
3.3.2.10 trans-beta-methyl-styrene oxide + H2O
-
 Mus musculus ?
-
 ?
3.3.2.10 trans-beta-methyl-styrene oxide + H2O
-
 Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.3.2.10 Cytosolic epoxide hydrolase
-
 Cavia porcellus
3.3.2.10 Cytosolic epoxide hydrolase
-
 Mus musculus
3.3.2.10 Cytosolic epoxide hydrolase
-
 Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.3.2.9 7.4 9 assay at Cavia porcellus
3.3.2.9 7.4 9 assay at Mus musculus
3.3.2.9 7.4 9 assay at Rattus norvegicus
3.3.2.10 7.4 9 assay at Cavia porcellus
3.3.2.10 7.4 9 assay at Mus musculus
3.3.2.10 7.4 9 assay at Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.3.2.9 7.4 9
-
 Cavia porcellus
3.3.2.9 7.4 9
-
 Mus musculus
3.3.2.9 7.4 9
-
 Rattus norvegicus
3.3.2.10 7.4 9
-
 Cavia porcellus
3.3.2.10 7.4 9
-
 Mus musculus
3.3.2.10 7.4 9
-
 Rattus norvegicus