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Literature summary extracted from

  • Fujimoto, D.; Koyama, T.; Tamiya, N.
    N-Acetyl-beta-alanine deacetylase in hog kidney (1968), Biochim. Biophys. Acta, 167, 407-413.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.5.1.21 2-mercaptoethanol 1 mM, activation 6% Sus sp.
3.5.1.21 L-cysteine 1 mM, activation 33% Sus sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.21 AgNO3 1 mM, 94% inhibition Sus sp.
3.5.1.21 CuSO4 1 mM, 57% inhibition Sus sp.
3.5.1.21 ethylenediaminetetraacetate 10 mM, 27% inhibition Sus sp.
3.5.1.21 HgCl2 1 mM, 100% inhibition Sus sp.
3.5.1.21 monoiodoacetate 1 mM, 73% inhibition Sus sp.
3.5.1.21 p-chloromercuribenzoate 1 mM, 100% inhibition Sus sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.1.21 7.5
-
 N-Acetyl-beta-alanine
-
 Sus sp.

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.21 Rattus rattus
-
 rat
-
3.5.1.21 Sus sp.
-
 pig
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.21 partially Sus sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.21 brain
-
 Rattus rattus
-
3.5.1.21 heart
-
 Rattus rattus
-
3.5.1.21 kidney
-
 Rattus rattus
-
3.5.1.21 kidney
-
 Sus sp.
-
3.5.1.21 liver
-
 Rattus rattus
-
3.5.1.21 spleen
-
 Rattus rattus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.5.1.21 33.5
-
 Sephadex G-200 eluate, 100fold purification Sus sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.21 N-acetyl-beta-alanine + H2O
-
 Sus sp. beta-alanine + acetate
-
 ?
3.5.1.21 N-acetyl-taurine + H2O reaction rate about 1/3 of that of acetyl-beta-alanine Sus sp. taurine + acetate
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.5.1.21 50 70 95% of enzyme activity remains after heating at 50°C for 2 min, 83% activity remains after 60°C heating for 2 min, 30% activity remains after heating at 70°C for 2 min Sus sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.1.21 7.6
-
-
 Sus sp.