Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kloor, D.; Fuchs, S.; Petroktistis, F.; Delabar, U.; Muhlbauer, B.; Quast, U.; Osswald, H.
    Effects of ions on adenosine binding and enzyme activity of purified S-adenosylhydrolase from bovine kidney (1998), Biochem. Pharmacol., 56, 1493-1496.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.13.2.1 phosphate
-
 Bos taurus

Application

EC Number Application Comment Organism
3.13.2.1 medicine antiviral drug design Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.13.2.1 CaCl2 reduces adenosine binding Bos taurus
3.13.2.1 Na+ reduces adenosine binding Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.13.2.1 0.0054
-
 adenosine phosphate added Bos taurus
3.13.2.1 0.0101
-
 adenosine no phosphate added Bos taurus
3.13.2.1 0.0103
-
 S-adenosyl-L-homocysteine phosphate added Bos taurus
3.13.2.1 0.0125
-
 S-adenosyl-L-homocysteine no phosphate added Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.13.2.1 S-adenosyl-L-homocysteine + H2O Bos taurus
-
 adenosine + L-homocysteine
-
 r

Organism

EC Number Organism UniProt Comment Textmining
3.13.2.1 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.13.2.1
-
 Bos taurus

Reaction

EC Number Reaction Comment Organism Reaction ID
3.13.2.1 S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine reaction equilibrium is in vitro strongly in direction of synthesis of S-adenosyl-L-homocysteine Bos taurus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.13.2.1 kidney
-
 Bos taurus
-

Storage Stability

EC Number Storage Stability Organism
3.13.2.1 -20°C Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.13.2.1 S-adenosyl-L-homocysteine + H2O
-
 Bos taurus adenosine + L-homocysteine
-
 r

Subunits

EC Number Subunits Comment Organism
3.13.2.1 tetramer
-
 Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
3.13.2.1 NAD+ essential for adenosine binding Bos taurus