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Literature summary extracted from

  • Osteras, M.; Boncompagni, E.; Vincent, N.; Poggi, M.C.; Le Rudulier, D.
    Presence of a gene encoding choline sulfatase in Sinorhizobium meliloti bet operon: choline-O-sulfate is metabolized into glycine betaine (1998), Proc. Natl. Acad. Sci. USA, 95, 11394-11399.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.6.6 choline formation of the enzyme is induced by Sinorhizobium meliloti
3.1.6.6 Choline sulfate formation of the enzyme is induced by Sinorhizobium meliloti

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.6.6 NaCl slight inhibition at high concentrations Sinorhizobium meliloti
3.1.6.6 phosphorylcholine competitive inhibition Sinorhizobium meliloti

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.6.6 choline sulfate + H2O Sinorhizobium meliloti is metabolized into glycine betaine choline + sulfate
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Organism

EC Number Organism UniProt Comment Textmining
3.1.6.6 Sinorhizobium meliloti
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.6 choline sulfate + H2O
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 Sinorhizobium meliloti choline + sulfate
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 ?
3.1.6.6 choline sulfate + H2O is metabolized into glycine betaine Sinorhizobium meliloti choline + sulfate
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3.1.6.6 phosphorylcholine + H2O less than 20% activity compared to choline sulfate as substrat Sinorhizobium meliloti choline + phosphate
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