Literature summary extracted from

Pieterson W.A.; Volwerk, J.J.; de Haas, G.H.
Interaction of phospholipase A2 and its zymogen with divalent metal ions (1974), Biochemistry, 13, 1439-1445.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.1.4	Ba2+	competitive inhibition	Sus scrofa
3.1.1.4	p-bromophenacyl bromide	-	Sus scrofa
3.1.1.4	Sr2+	competitive inhibition	Sus scrofa

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
3.1.1.4	Ba2+	prevents p-bromophenacyl bromide inactivation	Sus scrofa
3.1.1.4	Ba2+	diminishes susceptibility to trypsin attack	Sus scrofa
3.1.1.4	Ca2+	prevents p-bromophenacyl bromide inactivation	Sus scrofa
3.1.1.4	Ca2+	diminishes susceptibility to trypsin attack	Sus scrofa
3.1.1.4	Ca2+	only one Ca2+-binding site	Sus scrofa
3.1.1.4	Sr2+	diminishes susceptibility to trypsin attack and prevents p-bromophenacyl bromide inactivation	Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.1.1.4	phospholipids + H2O	Sus scrofa	-	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.1.4	Sus scrofa	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.1.4	pancreas	-	Sus scrofa	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.1.4	phospholipids + H2O	-	Sus scrofa	?	-	?

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Release 2023.1 (January 2023)