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Literature summary extracted from
- Isolation of phospholipase A2 from red cell membranes of sheep (1981), Methods Enzymol., 71, 690-698.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 3.1.1.4 | cholate restores full activity of SDS-treated PLA2 | Ovis aries |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.1.4 | plasma membrane | - |
Ovis aries | 5886 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.4 | Ca2+ | - |
Ovis aries |  |
| 3.1.1.4 | Mg2+ | can replace Ca2+, decreased activity | Ovis aries | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.4 | 12000 | - |
gel filtration | Ovis aries |
| 3.1.1.4 | 18500 | - |
SDS-PAGE | Ovis aries |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.4 | phosphatidylcholine + H2O | Ovis aries | - |
lysophosphatidylcholine + a fatty acid | - |
? | |
| 3.1.1.4 | phospholipids + H2O | Ovis aries | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.4 | Ovis aries | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.1.4 | gel filtration, affinity chromatography, 2835fold | Ovis aries |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.4 | erythrocyte | - |
Ovis aries | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.4 | 4.725 | - |
substrate: phosphatidylcholine | Ovis aries |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.4 | phosphatidylcholine + H2O | - |
Ovis aries | 1-acylglycerophosphocholine + fatty acid | - |
? | |
| 3.1.1.4 | phosphatidylcholine + H2O | - |
Ovis aries | lysophosphatidylcholine + a fatty acid | - |
? | |
| 3.1.1.4 | phosphatidylethanolamine + H2O | - |
Ovis aries | 1-acylglycerophosphorylethanolamine + fatty acid | - |
? | |
| 3.1.1.4 | phosphatidylglycerol + H2O | - |
Ovis aries | 1-acylglycerol + fatty acid | - |
? | |
| 3.1.1.4 | phosphatidylserine + H2O | - |
Ovis aries | 1-acylglycerophosphoserine + fatty acid | - |
? | |
| 3.1.1.4 | phospholipids + H2O | - |
Ovis aries | ? | - |
? | |
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Release 2023.1 (January 2023)
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