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Literature summary extracted from
- Inhibition of dihydrofolate synthetase by folate, homofolate, pteroate and homopteroate and their reduced forms (1976), Biochim. Biophys. Acta, 422, 419-426.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 6.3.2.12 | 7,8-dihydrofolate | - |
Escherichia coli |  |
| 6.3.2.12 | dihydrohomopteroic acid | - |
Escherichia coli | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 6.3.2.12 | Escherichia coli | - |
B | - |
| 6.3.2.12 | Escherichia coli B / ATCC 11303 | - |
B | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 6.3.2.12 | ATP + 7,8-dihydropteroate + L-Glu | - |
Escherichia coli | ADP + phosphate + 7,8-dihydrofolate | - |
? | |
| 6.3.2.12 | ATP + 7,8-dihydropteroate + L-Glu | - |
Escherichia coli B / ATCC 11303 | ADP + phosphate + 7,8-dihydrofolate | - |
? | |
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