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Literature summary for 7.6.2.9 extracted from
- Three transport systems for the osmoprotectant glycine betaine operate in Bacillus subtilis: characterization of OpuD (1996), J. Bacteriol., 178, 5071-5079.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| opuD | Bacillus subtilis |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0024 | - |
glycine betaine | OpuA | Bacillus subtilis |  |
| 0.0051 | - |
glycine betaine | OpuC, without NaCl | Bacillus subtilis | |
| 0.006 | - |
glycine betaine | OpuC, in presence of 0.4 M NaCl | Bacillus subtilis | |
| 0.0095 | - |
glycine betaine | OpuD, without NaCl | Bacillus subtilis | |
| 0.013 | - |
glycine betaine | OpuD, in presence of 0.4 M NaCl | Bacillus subtilis | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | high osmolarity activates | Bacillus subtilis |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 56130 | - |
x * 56130, calculation from nucleotide sequence | Bacillus subtilis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + glycine betaine/out | Bacillus subtilis | high osmolarity stimulates de novo synthesis of OpuD and activates preeixisting OpuD proteins to achieve maximal glycine betaine uptake activity | ADP + phosphate + glycine betaine/in | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
three transport systems for the osmoprotectant glycine betaine: OpuA, OpuC and Opu D | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + glycine betaine/out | - |
Bacillus subtilis | ADP + phosphate + glycine betaine/in | - |
? | |
| ATP + H2O + glycine betaine/out | high osmolarity stimulates de novo synthesis of OpuD and activates preeixisting OpuD proteins to achieve maximal glycine betaine uptake activity | Bacillus subtilis | ADP + phosphate + glycine betaine/in | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 56130, calculation from nucleotide sequence | Bacillus subtilis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| OpuD | - |
Bacillus subtilis |
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Release 2023.1 (January 2023)
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