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Literature summary for 7.4.2.1 extracted from

  • Aoki, J.I.; Muxel, S.M.; Zampieri, R.A.; Acuna, S.M.; Fernandes, J.C.R.; Vanderlinde, R.H.; Sales, M.C.O.P.; Floeter-Winter, L.M.
    L-arginine availability and arginase activity Characterization of amino acid permease 3 in Leishmania amazonensis (2017), PLoS Negl. Trop. Dis., 11, e0006025 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.4.2.1

Localization

Localization Comment Organism GeneOntology No. Textmining
glycosome
-
 Leishmania amazonensis 20015
-
plasma membrane
-
 Leishmania amazonensis 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania amazonensis
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania amazonensis MHOM/BR/1973/2269
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?

Organism

Organism UniProt Comment Textmining
Leishmania amazonensis
-
-
-
Leishmania amazonensis MHOM/BR/1973/2269
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
amastigote
-
 Leishmania amazonensis
-
promastigote
-
 Leishmania amazonensis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania amazonensis ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania amazonensis MHOM/BR/1973/2269 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?

Synonyms

Synonyms Comment Organism
aap3
-
 Leishmania amazonensis
amino acid permease 3
-
 Leishmania amazonensis

Expression

Organism Comment Expression
Leishmania amazonensis an increase of temperature from 25 to 34°C increases the enzyme level in plasma membrane, independently of pH and L-arginine availability up