Literature summary for 7.2.2.13 extracted from

Maiti, A.K.; Paul, G.; Maity, B.; Mazumdar, D.; Saha, N.C.
Chromium III exposure inhibits brain Na+K+ATPase activity of Clarias batrachus L. involving lipid peroxidation and deficient mitochondrial electron transport chain activity (2009), Bull. Environ. Contam. Toxicol., 83, 479-483.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Clarias batrachus	16020	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Cr3+	causes oxidative stress in fish and leads to reduced enzyme activity in the brain, mechanism, overview. The level of ATP production in brain mitochondria may be an important criteria in the CrIII induced inhibition of Na+K+ATPase activity of fish brain, reduction of Na+K+ATPase activity is partially mediated by lipid peroxidation and deficient mitochondrial electron transport chain activity. Also direct interaction of CrIII ion with the -SH group of Na+K+ATPase enzyme might play a role	Clarias batrachus

Organism

Organism	UniProt	Comment	Textmining
Clarias batrachus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Clarias batrachus	-

Synonyms

Synonyms	Comment	Organism
Na+K+ATPase	-	Clarias batrachus

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Release 2023.1 (January 2023)