Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Arabidopsis thaliana | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
diphosphate + H2O + H+[side 1] | Arabidopsis thaliana | - |
2 phosphate + H+[side 2] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
seedling | - |
Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
diphosphate + H2O + H+[side 1] | - |
Arabidopsis thaliana | 2 phosphate + H+[side 2] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
H+-PPase | - |
Arabidopsis thaliana |
inorganic pyrophosphatase | - |
Arabidopsis thaliana |
PPase | - |
Arabidopsis thaliana |
proton-translocating vacuolar PPase | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
malfunction | defects in PPase activity cause severe developmental defects and/or growth arrest in several organisms. The fugu5 mutant phenotype, caused by a defect in H+-PPase activity, shows a postgerminative growth phenotype, but is rescued by complementation with the yeast cytosolic PPase IPP1, overview. Increased cytosolic PPi levels Impaired postgerminative development in fugu5 by inhibiting gluconeogenesis | Arabidopsis thaliana |
metabolism | implication of H+-PPase in postgerminative oilseed metabolism, overview | Arabidopsis thaliana |
physiological function | proton-translocating vacuolar PPase, H+-PPase, uses the energy of diphosphate hydrolysis to acidify the vacuole in higher plants. H+-PPase is a master regulator of cytosolic diphosphate homeostasis, another role of H+-PPase in plants is vacuolar acidification, the role of H+-PPase as a proton-pump is negligible | Arabidopsis thaliana |