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Literature summary for 7.1.3.1 extracted from

  • Ferjani, A.; Segami, S.; Horiguchi, G.; Sakata, A.; Maeshima, M.; Tsukaya, H.
    Regulation of pyrophosphate levels by H+-PPase is central for proper resumption of early plant development (2012), Plant Signal. Behav., 7, 38-42.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Arabidopsis thaliana 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
diphosphate + H2O + H+[side 1] Arabidopsis thaliana
-
2 phosphate + H+[side 2]
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
seedling
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphosphate + H2O + H+[side 1]
-
Arabidopsis thaliana 2 phosphate + H+[side 2]
-
?

Synonyms

Synonyms Comment Organism
H+-PPase
-
Arabidopsis thaliana
inorganic pyrophosphatase
-
Arabidopsis thaliana
PPase
-
Arabidopsis thaliana
proton-translocating vacuolar PPase
-
Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction defects in PPase activity cause severe developmental defects and/or growth arrest in several organisms. The fugu5 mutant phenotype, caused by a defect in H+-PPase activity, shows a postgerminative growth phenotype, but is rescued by complementation with the yeast cytosolic PPase IPP1, overview. Increased cytosolic PPi levels Impaired postgerminative development in fugu5 by inhibiting gluconeogenesis Arabidopsis thaliana
metabolism implication of H+-PPase in postgerminative oilseed metabolism, overview Arabidopsis thaliana
physiological function proton-translocating vacuolar PPase, H+-PPase, uses the energy of diphosphate hydrolysis to acidify the vacuole in higher plants. H+-PPase is a master regulator of cytosolic diphosphate homeostasis, another role of H+-PPase in plants is vacuolar acidification, the role of H+-PPase as a proton-pump is negligible Arabidopsis thaliana