Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(1R,1'R)-1,1'-(2R,2'R,5R,5'R)-octahydro-2,2'-bifuran-5,5'-diylbis(5-[4-[(E)-(4-butylphenyl)diazenyl]phenoxy]pentan-1-ol) | 48 nM, 70% inhibition | Bos taurus | |
(1R,1'R)-1,1'-(2R,2'R,5R,5'R)-octahydro-2,2'-bifuran-5,5'-diylbis(5-[4-[(Z)-(4-butylphenyl)diazenyl]phenoxy]pentan-1-ol) | 48 nM, 70% inhibition | Bos taurus | |
(1R,1'R)-1,1'-(2R,2'R,5R,5'R)-octahydro-2,2'-bifuran-5,5'-diylbis[6-(2-butylphenoxy)hexan-1-ol] | IC50: 1000 nM | Bos taurus | |
(1R,1'R)-1,1'-(2R,2'R,5R,5'R)-octahydro-2,2'-bifuran-5,5'-diylbis[6-(4-butylphenoxy)hexan-1-ol] | IC50: 0.83 nM | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Bos taurus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + ubiquinone | - |
Bos taurus | NAD+ + ubiquinol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
complex I | - |
Bos taurus |
NADH-ubiquinone oxidoreductase | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Bos taurus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00000083 | - |
IC50: 0.83 nM | Bos taurus | (1R,1'R)-1,1'-(2R,2'R,5R,5'R)-octahydro-2,2'-bifuran-5,5'-diylbis[6-(4-butylphenoxy)hexan-1-ol] | |
0.001 | - |
IC50: 1000 nM | Bos taurus | (1R,1'R)-1,1'-(2R,2'R,5R,5'R)-octahydro-2,2'-bifuran-5,5'-diylbis[6-(2-butylphenoxy)hexan-1-ol] |