BRENDA - Enzyme Database
show all sequences of 6.4.1.5

Plant biotin-containing carboxylases

Nikolau, B.J.; Ohlrogge, J.B.; Wurtele, E.S.; Arch. Biochem. Biophys. 414, 211-222 (2003) View publication on PubMed

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.008
-
ATP
-
Zea mays
0.064
-
geranoyl-CoA
-
Zea mays
0.6
-
HCO3-
-
Zea mays
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
plastid
-
Zea mays
9536
-
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
63000
-
x * 75000 + x * 63000, only the larger subunit is biotinylated
Pseudomonas sp.
75000
-
x * 75000 + x * 63000, only the larger subunit is biotinylated
Pseudomonas sp.
550000
-
about
Pseudomonas sp.
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
additional information
Zea mays
may be involved in isoprenoid metabolism, catabolism of acyclic isoprenoids
?
-
Zea mays
?
additional information
Pseudomonas sp.
may be involved in isoprenoid metabolism, catabolism of acyclic isoprenoids
?
-
Pseudomonas sp.
?
Organism
Organism
UniProt
Commentary
Textmining
Pseudomonas sp.
-
-
-
Zea mays
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
ATP + geranoyl-CoA + HCO3-
two-step reaction, ATP-dependent carboxylation of the methyl group that is proximal to the carboxyl end of geranoyl-CoA, domain structure
649484
Zea mays
ADP + phosphate + 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA
formation of gamma-carboxygeranoyl-CoA
649484
Zea mays
?
ATP + geranoyl-CoA + HCO3-
two-step reaction, ATP-dependent carboxylation of the methyl group that is proximal to the carboxyl end of geranoyl-CoA, domain structure
649484
Pseudomonas sp.
ADP + phosphate + 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA
formation of gamma-carboxygeranoyl-CoA
649484
Pseudomonas sp.
?
additional information
may be involved in isoprenoid metabolism, catabolism of acyclic isoprenoids
649484
Zea mays
?
-
649484
Zea mays
?
additional information
may be involved in isoprenoid metabolism, catabolism of acyclic isoprenoids
649484
Pseudomonas sp.
?
-
649484
Pseudomonas sp.
?
Subunits
Subunits
Commentary
Organism
?
x * 75000 + x * 63000, only the larger subunit is biotinylated
Pseudomonas sp.
More
biotin-containing subunit of 122 kDa
Zea mays
Synonyms
Synonyms
Commentary
Organism
GCCase
-
Zea mays
GCCase
-
Pseudomonas sp.
Cofactor
Cofactor
Commentary
Organism
Structure
biotin
biotin-dependent enzyme
Zea mays
biotin
biotin-dependent enzyme, only the 75 kDa subunit is biotinylated
Pseudomonas sp.
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
biotin
biotin-dependent enzyme
Zea mays
biotin
biotin-dependent enzyme, only the 75 kDa subunit is biotinylated
Pseudomonas sp.
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.008
-
ATP
-
Zea mays
0.064
-
geranoyl-CoA
-
Zea mays
0.6
-
HCO3-
-
Zea mays
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
plastid
-
Zea mays
9536
-
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
63000
-
x * 75000 + x * 63000, only the larger subunit is biotinylated
Pseudomonas sp.
75000
-
x * 75000 + x * 63000, only the larger subunit is biotinylated
Pseudomonas sp.
550000
-
about
Pseudomonas sp.
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
additional information
Zea mays
may be involved in isoprenoid metabolism, catabolism of acyclic isoprenoids
?
-
Zea mays
?
additional information
Pseudomonas sp.
may be involved in isoprenoid metabolism, catabolism of acyclic isoprenoids
?
-
Pseudomonas sp.
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
ATP + geranoyl-CoA + HCO3-
two-step reaction, ATP-dependent carboxylation of the methyl group that is proximal to the carboxyl end of geranoyl-CoA, domain structure
649484
Zea mays
ADP + phosphate + 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA
formation of gamma-carboxygeranoyl-CoA
649484
Zea mays
?
ATP + geranoyl-CoA + HCO3-
two-step reaction, ATP-dependent carboxylation of the methyl group that is proximal to the carboxyl end of geranoyl-CoA, domain structure
649484
Pseudomonas sp.
ADP + phosphate + 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA
formation of gamma-carboxygeranoyl-CoA
649484
Pseudomonas sp.
?
additional information
may be involved in isoprenoid metabolism, catabolism of acyclic isoprenoids
649484
Zea mays
?
-
649484
Zea mays
?
additional information
may be involved in isoprenoid metabolism, catabolism of acyclic isoprenoids
649484
Pseudomonas sp.
?
-
649484
Pseudomonas sp.
?
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 75000 + x * 63000, only the larger subunit is biotinylated
Pseudomonas sp.
More
biotin-containing subunit of 122 kDa
Zea mays
Other publictions for EC 6.4.1.5
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
745854
Jurado
Structure and substrate selec ...
Pseudomonas fluorescens, Pseudomonas aeruginosa, Pseudomonas aeruginosa DSM 22644
Nat. Commun.
6
8986
2015
-
-
-
2
-
-
-
-
-
-
-
-
-
6
-
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-
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2
-
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2
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-
-
-
-
-
-
-
-
-
-
-
-
-
692864
Aguilar
Substrate specificity of the 3 ...
Pseudomonas aeruginosa
J. Bacteriol.
190
4888-4893
2008
-
-
1
-
-
-
-
3
-
-
2
1
-
5
-
-
1
-
1
-
-
-
3
1
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
3
-
-
2
1
-
-
-
1
1
-
-
-
3
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
671453
Aguilar
The atu and liu clusters are i ...
Pseudomonas aeruginosa
Appl. Environ. Microbiol.
72
2070-2079
2006
-
-
-
-
-
-
-
-
-
-
-
1
-
9
-
-
-
-
-
-
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-
1
-
-
-
-
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-
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-
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1
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1
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-
-
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-
-
-
-
-
-
-
-
-
-
671465
Foerster-Fromme
Identification of genes and pr ...
Pseudomonas aeruginosa
Appl. Environ. Microbiol.
72
4819-4828
2006
-
-
-
-
-
-
-
-
-
-
-
1
-
13
-
-
-
-
-
-
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-
1
-
2
-
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-
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-
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1
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-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
662790
Hoschle
Methylcrotonyl-CoA and geranyl ...
Pseudomonas aeruginosa
Microbiology
151
3649-3656
2005
-
-
-
-
-
-
-
-
-
-
-
2
-
6
-
-
-
-
-
-
-
-
2
-
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-
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2
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-
2
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-
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-
-
-
-
-
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-
-
-
-
660754
Diaz-Perez
The gnyRDBHAL cluster is invol ...
Pseudomonas aeruginosa
Appl. Environ. Microbiol.
70
5102-5110
2004
-
-
-
-
-
-
-
-
-
-
-
1
-
4
-
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2
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1
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2
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-
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-
-
-
-
649484
Nikolau
Plant biotin-containing carbox ...
Pseudomonas sp., Zea mays
Arch. Biochem. Biophys.
414
211-222
2003
-
-
-
-
-
-
-
3
1
-
3
2
-
4
-
-
-
-
-
-
-
-
4
2
2
-
-
-
-
-
-
-
2
-
-
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-
-
2
-
-
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-
-
-
3
1
-
3
2
-
-
-
-
-
-
-
-
4
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
649418
Guan
Geranoyl-CoA carboxylase: a no ...
Daucus carota, Glycine max, Zea mays
Arch. Biochem. Biophys.
362
12-21
1999
-
-
-
-
-
-
1
3
2
1
1
3
-
15
-
-
1
-
-
-
4
-
7
1
3
-
-
-
-
1
1
-
3
-
-
-
-
-
-
3
-
-
-
-
1
-
3
2
1
1
3
-
-
-
1
-
-
4
-
7
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
1886
Fall
3-Methylcrotonyl-CoA and geran ...
Pseudomonas citronellolis
Methods Enzymol.
71
791-799
1981
-
-
-
-
-
-
-
-
-
-
3
-
-
1
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-
1
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1
1
5
1
-
-
-
1
-
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-
1
-
-
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-
1
-
-
-
-
-
-
-
-
-
3
-
-
-
-
1
-
-
1
1
5
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1905
Cantwell
Biodegradation of acyclic isop ...
Pseudomonas aeruginosa, Pseudomonas citronellolis, Pseudomonas mendocina
J. Bacteriol.
135
324-333
1978
-
-
-
-
-
-
-
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-
3
-
3
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4
-
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3
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4
-
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1888
Fall
Acyl-coenzyme A carboxylases. ...
Pseudomonas citronellolis
Biochemistry
16
4000-4005
1977
-
-
-
-
-
-
1
-
-
-
3
-
-
1
-
-
1
-
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-
1
1
2
1
-
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1
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-
1
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1
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-
3
-
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-
1
-
-
1
1
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1871
Hector
Multiple acyl-coenzyme A carbo ...
Pseudomonas citronellolis
Biochemistry
15
3465-3472
1976
-
-
-
-
-
-
-
-
-
-
-
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-
2
-
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1
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1
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1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1889
Hector
Evidence for distinct 3-methyl ...
Pseudomonas citronellolis
Biochem. Biophys. Res. Commun.
71
746-753
1976
-
-
-
-
-
-
-
-
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1
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1
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1
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1
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1
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-
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-
-
-
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-
-
-
-
1904
Seubert
-
Untersuchungen über den bakte ...
Pseudomonas citronellolis
Biochem. Z.
338
265-275
1963
-
-
-
-
-
-
1
-
-
-
-
1
-
1
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-
1
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1
4
-
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1
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1
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1
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1
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1
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1
4
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