Cloned (Comment) | Organism |
---|---|
- |
Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
albizziin | - |
Escherichia coli | |
Glu | - |
Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.03 | - |
L-Gln | 5'-phosphoribosylformylglycinamidine | Escherichia coli | |
0.0468 | - |
(-)carbocyclic-5'-phosphoribosylformylglycinamidine | - |
Escherichia coli | |
1 | - |
NH4+ | - |
Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | maximal activity at 10 mM K+ | Escherichia coli | |
Mg2+ | maximal activation at 20 mM | Escherichia coli |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
141418 | - |
x * 141418, calculation from nucleotide sequence | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Escherichia coli |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
2.15 | - |
- |
Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5'-phosphoribosylformylglycinamide + L-Gln + H2O | - |
Escherichia coli | ADP + phosphate + 5'-phosphoribosylformylglycinamidine + L-Glu | - |
? | |
ATP + 5'-phosphoribosylformylglycinamide + NH4+ + H2O | - |
Escherichia coli | ADP + phosphate + 5'-phosphoribosylformylglycinamidine | - |
? | |
ATP + carbocyclic-5'-phosphoribosylformylglycinamide + L-Gln + H2O | (+/-)carbocyclic-5'-phosphoribosylformylglycinamide and (-)5'-phosphoribosylformylglycinamide at 10% of the activity relative to 5'-phosphoribosylformylglycinamide | Escherichia coli | ADP + phosphate + carbocyclic-5'-phosphoribosylformylglycinamidine + L-Glu | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 141418, calculation from nucleotide sequence | Escherichia coli |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.05 | - |
NH4+ | - |
Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
- |
Escherichia coli |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.2 | 8 | about 50% of maximal activity at pH 6.2 and 8.0 | Escherichia coli |