Cloned (Comment) | Organism |
---|---|
expressed as FLAG epitope-tagged protein in HEK-293T and CHO-K1 cells | Mus musculus |
expressed as FLAG epitope-tagged protein in HEK-293T and CHO-K1 cells. Because hexahistidine-tagged Escherichia coli-expressed enzyme using bacterial expressed protein | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
42000 | - |
x * 42000, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + N-acetyl-L-aspartate + 2 L-glutamate | Mus musculus | - |
2 ADP + 2 phosphate + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate | - |
? | |
ATP + N-acetyl-L-aspartate + L-glutamate | Mus musculus | - |
ADP + phosphate + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Mus musculus | Q6PFX8 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
brain stem | - |
Mus musculus | - |
central nervous system | highest expression levels in the brain stem and spinal cord, almost undetectable in the neocortex | Mus musculus | - |
cerebellum | - |
Mus musculus | - |
cerebellum | strong expression is restricted to deep cerebellar nuclei | Mus musculus | - |
forebrain | - |
Mus musculus | - |
kidney | - |
Mus musculus | - |
sciatic nerve | - |
Mus musculus | - |
spinal cord | - |
Mus musculus | - |
spinal cord | expression is found in the ventral and dorsal horns of gray matter in laminae III to X, but is low or absent in laminae I and II | Mus musculus | - |
testis | - |
Mus musculus | - |
thymus | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + N-acetyl-L-aspartate + 2 L-glutamate | - |
Mus musculus | 2 ADP + 2 phosphate + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate | - |
? | |
2 ATP + N-acetyl-L-aspartate + 2 L-glutamate | the enzyme also has the activity of EC 6.3.2.41, N-acetylaspartylglutamate synthase | Mus musculus | 2 ADP + 2 phosphate + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate | - |
? | |
ATP + N-acetyl-L-aspartate + L-glutamate | - |
Mus musculus | ADP + phosphate + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 42000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
N-acetylaspartylglutamate synthetase II | - |
Mus musculus |
N-acetylaspartylglutamylglutamate synthetase | - |
Mus musculus |
NAAG synthetase II | - |
Mus musculus |
NAAG(2) synthase | - |
Mus musculus |
NAAGS-II | - |
Mus musculus |
RIMKLA | gene name, ambiguous | Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |