Literature summary for 6.2.1.72 extracted from

Chan, Y.; Boyne II, M.; Podevels, A.; Klimowicz, A.; Handelsman, J.; Kelleher, N.; Thomas, M.
Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units (2006), Proc. Natl. Acad. Sci. USA, 103, 14349-14354 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Bacillus cereus

Organism

Organism	UniProt	Comment	Textmining
Bacillus cereus	Q7BQ71	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-serine + holo-[L-seryl-carrier protein ZmaH]	-	Bacillus cereus	AMP + diphosphate + L-seryl-[L-seryl-carrier protein ZmaH]	-	?
additional information	no substrates: L-2,3-diaminopropionate, L-Thr, Gly, and L-Cys. No acceptor: ZmaD	Bacillus cereus	?	-	-

Synonyms

Synonyms	Comment	Organism
zmaJ	-	Bacillus cereus

General Information

General Information	Comment	Organism
physiological function	during biosynthesis of zwittermicin A, ZmaJ tethers L-Ser to ZmaH, and the seryl-acyl carrier protein is then oxidized to aminomalonyl-acyl carrier protein	Bacillus cereus

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Release 2023.1 (January 2023)