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Literature summary for 5.6.1.7 extracted from
- Divalent cations stabilize GroEL under conditions of oxidative stress (2008), Biochem. Biophys. Res. Commun., 368, 625-630.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | is found to protect against proteolysis of a form of GroEL, ox-GroEL, prepared by exposing GroEL to hydroxide peroxide, induces a conformational change | Escherichia coli |  |
| Mg2+ | is found to protect against proteolysis of a form of GroEL, ox-GroEL, prepared by exposing GroEL to hydroxide peroxide, induces a conformational change | Escherichia coli | |
| Mn2+ | is found to protect against proteolysis of a form of GroEL, ox-GroEL, prepared by exposing GroEL to hydroxide peroxide, induces a conformational change | Escherichia coli | |
| Ni2+ | is found to protect against proteolysis of a form of GroEL, ox-GroEL, prepared by exposing GroEL to hydroxide peroxide, induces a conformational change | Escherichia coli | |
| Zn2+ | is found to protect against proteolysis of a form of GroEL, ox-GroEL, prepared by exposing GroEL to hydroxide peroxide, induces a conformational change | Escherichia coli | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 57260 | - |
monomer | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + a folded polypeptide | Escherichia coli | - |
ADP + phosphate + an unfolded polypeptide | - |
ir | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| GroEL is purified from lysates of Escherichia coli bearing the multicopy plasmid pGroESL | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + a folded polypeptide | - |
Escherichia coli | ADP + phosphate + an unfolded polypeptide | - |
ir | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homotetradecamer | 14 monomers are arranged as two stacked heptameric rings, with a central cavity at each end | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GroEl | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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