Cloned (Comment) | Organism |
---|---|
adaptor-p80 fragments expressed in Escherichia coli BL21(DE3), GST tagged p60-katanin expressed in Escherichia coli JM109 | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
K255A | no ATPase activity | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | inhibits microtuble severing activity | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q9WV86 | - |
- |
Purification (Comment) | Organism |
---|---|
GST tagged p60-katanin purified using glutathione-Sepharose | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | binding of either microtuble or C-terminal domain of adaptor-p80 stimulates the ATPase activity of p60-katanin | Mus musculus | ADP + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterodimer | p60-katanin (hexameric ring), adaptor-p80 | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
katanin | - |
Mus musculus |
P60-katanin | - |
Mus musculus |