Cloned (Comment) | Organism |
---|---|
expression in Pichia pastoris | Homo sapiens |
expression in Saccharomyces cerevisiae | Trypanosoma cruzi |
expression in Saccharomyces cerevisiae | Pneumocystis carinii |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-biphenyl-4-ylpropyl ether | comparison with inhibitory effect on Trypanosoma cruzi, Saccharomyces cerevisiae, and Pneumocystis carinii enzyme | Homo sapiens | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-biphenyl-4-ylpropyl ether | comparison with inhibitory effect on Trypanosoma cruzi, Saccharomyces cerevisiae, and human enzyme | Pneumocystis carinii | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-biphenyl-4-ylpropyl ether | comparison with inhibitory effect on Trypanosoma cruzi, Pneumocystis carini, and human enzyme | Saccharomyces cerevisiae | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-biphenyl-4-ylpropyl ether | comparison with inhibitory effect on Pneumocystis carinii, Saccharomyces cerevisiae, and human enzyme | Trypanosoma cruzi | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-phenylpropyl ether | comparison with inhibitory effect on Trypanosoma cruzi, Saccharomyces cerevisiae, and Pneumocystis carinii enzyme | Homo sapiens | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-phenylpropyl ether | comparison with inhibitory effect on Trypanosoma cruzi, Saccharomyces cerevisiae, and human enzyme | Pneumocystis carinii | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-phenylpropyl ether | comparison with inhibitory effect on Trypanosoma cruzi, Pneumocystis carini, and human enzyme | Saccharomyces cerevisiae | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-phenylpropyl ether | comparison with inhibitory effect on Pneumocystis carinii, Saccharomyces cerevisiae, and human enzyme | Trypanosoma cruzi | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl hexyl ether | comparison with inhibitory effect on Trypanosoma cruzi, Saccharomyces cerevisiae, and Pneumocystis carinii enzyme | Homo sapiens | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl hexyl ether | comparison with inhibitory effect on Trypanosoma cruzi, Saccharomyces cerevisiae, and human enzyme | Pneumocystis carinii | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl hexyl ether | comparison with inhibitory effect on Trypanosoma cruzi, Pneumocystis carini, and human enzyme | Saccharomyces cerevisiae | |
(2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl hexyl ether | comparison with inhibitory effect on Pneumocystis carinii, Saccharomyces cerevisiae, and human enzyme | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Pneumocystis carinii | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Trypanosoma cruzi | - |
- |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00033 | - |
- |
Pneumocystis carinii | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-phenylpropyl ether | |
0.00036 | - |
- |
Pneumocystis carinii | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl hexyl ether | |
0.00045 | - |
- |
Saccharomyces cerevisiae | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-phenylpropyl ether | |
0.00047 | - |
- |
Trypanosoma cruzi | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-phenylpropyl ether | |
0.00085 | - |
- |
Homo sapiens | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl hexyl ether | |
0.0011 | - |
- |
Homo sapiens | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-phenylpropyl ether | |
0.0017 | - |
- |
Pneumocystis carinii | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-biphenyl-4-ylpropyl ether | |
0.00178 | - |
- |
Saccharomyces cerevisiae | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl hexyl ether | |
0.0027 | - |
- |
Trypanosoma cruzi | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl hexyl ether | |
0.0045 | - |
- |
Homo sapiens | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-biphenyl-4-ylpropyl ether | |
0.0074 | - |
- |
Trypanosoma cruzi | (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-yl 3-biphenyl-4-ylpropyl ether |