Protein Variants | Comment | Organism |
---|---|---|
additional information | proteins containing residues 1-285 and residues 1-300 retain full chorismate mutase activity and prephenate dehydratase activity, but exhibit no feedback inhibition. Proteins containing residues 101-386 and residues 101-300 retain full prephenate dehydratase activity, but lack mutase activity | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
bifunctional enzyme chorismate mutase/prephenate dehydratase | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Chorismate | - |
Escherichia coli | Prephenate | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
54 | - |
1 h, 50% loss of activity, wild-type enzyme | Escherichia coli |
58 | - |
1 h, 50% inactivation, genetically engineered enzyme with amino acid residues 1-285 | Escherichia coli |
62 | - |
1 h, 50% inactivation, genetically engineered enzyme with amino acid residues 1-300 | Escherichia coli |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
39 | - |
chorismate | wild-type enzyme | Escherichia coli | |
40.7 | - |
chorismate | genetically engineered enzyme containg the amino acid residues 1-300 | Escherichia coli | |
44.3 | - |
chorismate | genetically engineered enzyme containg the amino acid residues 1-285 | Escherichia coli |