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Literature summary for 5.4.99.33 extracted from

  • Shibuya, M.; Adachi, S.; Ebizuka, Y.
    Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis (2004), Tetrahedron, 60, 6995-7003.
No PubMed abstract available
Search for more literature for 5.4.99.33

Cloned(Commentary)

Cloned (Comment) Organism
expressed in lanosterol synthase deficient (erg7) Saccharomyces cerevisiae strain GIL77 Cucurbita pepo

Protein Variants

Protein Variants Comment Organism
I489V the mutation does not result in the change of product-specificity Cucurbita pepo
L488P the mutation does not result in the change of product-specificity Cucurbita pepo
LI488/489PV the mutation does not result in the change of product-specificity Cucurbita pepo

Organism

Organism UniProt Comment Textmining
Cucurbita pepo Q6BE24
-
-

Source Tissue

Source Tissue Comment Organism Textmining
seedling
-
 Cucurbita pepo
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-squalene-2,3-epoxide
-
 Cucurbita pepo cucurbitadienol
-
 ?

Synonyms

Synonyms Comment Organism
CPQ
-
 Cucurbita pepo

General Information

General Information Comment Organism
metabolism cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis Cucurbita pepo