BRENDA - Enzyme Database
show all sequences of 5.4.99.32

Protostadienol biosynthesis and metabolism in the pathogenic fungus Aspergillus fumigatus

Lodeiro, S.; Xiong, Q.; Wilson, W.; Ivanova, Y.; Smith, M.; May, G.; Matsuda, S.; Org. Lett. 11, 1241-1244 (2009)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Aspergillus fumigatus
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Aspergillus fumigatus Af293
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Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(3S)-oxidosqualene
-
716417
Aspergillus fumigatus
(17Z)-protosta-17(20),24-dien-3beta-ol + (17Z)-protosta-13(17),24-dien-3beta-ol
product yield is 95% (17Z)-protosta-17(20),24-dien-3beta-ol (i.e. protostadienol) and 5% (17Z)-protosta-13(17),24-dien-3beta-ol
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-
?
(3S)-oxidosqualene
-
716417
Aspergillus fumigatus Af293
(17Z)-protosta-17(20),24-dien-3beta-ol + (17Z)-protosta-13(17),24-dien-3beta-ol
product yield is 95% (17Z)-protosta-17(20),24-dien-3beta-ol (i.e. protostadienol) and 5% (17Z)-protosta-13(17),24-dien-3beta-ol
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-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(3S)-oxidosqualene
-
716417
Aspergillus fumigatus
(17Z)-protosta-17(20),24-dien-3beta-ol + (17Z)-protosta-13(17),24-dien-3beta-ol
product yield is 95% (17Z)-protosta-17(20),24-dien-3beta-ol (i.e. protostadienol) and 5% (17Z)-protosta-13(17),24-dien-3beta-ol
-
-
?
(3S)-oxidosqualene
-
716417
Aspergillus fumigatus Af293
(17Z)-protosta-17(20),24-dien-3beta-ol + (17Z)-protosta-13(17),24-dien-3beta-ol
product yield is 95% (17Z)-protosta-17(20),24-dien-3beta-ol (i.e. protostadienol) and 5% (17Z)-protosta-13(17),24-dien-3beta-ol
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-
?
Other publictions for EC 5.4.99.32
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
714021
Kimura
Protostadienol synthase from A ...
Aspergillus fumigatus
Biochem. Biophys. Res. Commun.
391
899-902
2010
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716417
Lodeiro
Protostadienol biosynthesis an ...
Aspergillus fumigatus, Aspergillus fumigatus Af293
Org. Lett.
11
1241-1244
2009
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