Cloned (Comment) | Organism |
---|---|
- |
Pyrococcus furiosus |
- |
Methanocaldococcus jannaschii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methanocaldococcus jannaschii | - |
- |
- |
Pyrococcus furiosus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
tRNA uridine55 | the bifunctional enzyme can act as synthase for both tRNA pseudouridine54 and pseudouridine55. The two modifications seem to occur independently. Unlike bacterial TruB and yeast Pus4, archaeal Pus10 does not require a U54*A58 reverse Hoogstein base pair and pyrimidine at position 56 to convert tRNA uridine55 to pseudouridine55. Although the T(PSI)PSI-arm of tRNA is a good substrate for both pseudouridine54 and pseudouridine55 synthesis by Mj-Pus10, the production of pseudouridine55 is more efficient than that of pseudouridine54 in this substrate. This contrasts with full-size tRNA substrates, where syntheses of pseudourines appear to be equally efficient | Methanocaldococcus jannaschii | tRNA pseudouridine55 | - |
? | |
tRNA uridine55 | uridine55 in Haloferax volcanii tRNATrp. The bifunctional enzyme can act as synthase for both tRNA pseudouridine54 and pseudouridine55. The two modifications seem to occur independently. Unlike bacterial TruB and yeast Pus4, archaeal Pus10 does not require a U54*A58 reverse Hoogstein base pair and pyrimidine at position 56 to convert tRNA U55 to C55 | Pyrococcus furiosus | tRNA pseudouridine55 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Mj-Pus10 | - |
Methanocaldococcus jannaschii |
PSI55 synthase | - |
Methanocaldococcus jannaschii |
Pus10 | - |
Pyrococcus furiosus |
Pus10 | - |
Methanocaldococcus jannaschii |