Application | Comment | Organism |
---|---|---|
medicine | it is hypothesized that the combination of prostacyclin synthase overexpression and epidermal growth factor receptor tyrosine kinase inhibitor, EGFR TKI, would lead to augmented chemoprevention for lung cancer | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | Mus musculus | - |
Prostaglandin I2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
transgenic mice are developed using a construct consisting of the human SP-C promotor and full-length rat prostacyclin synthase cDNA | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | - |
Mus musculus | Prostaglandin I2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PGIS | - |
Mus musculus |
prostacyclin synthase | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | for overexpression of prostacyclin synthase transgenic mice, carrying the rat prostacyclin synthase gene, are developed | up |