Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.6.1.2 extracted from

  • Nishida, T.; Yu, J.D.; Minamishima, S.; Sips, P.Y.; Searles, R.J.; Buys, E.S.; Janssens, S.; Brouckaert, P.; Bloch, K.D.; Ichinose, F.
    Protective effects of nitric oxide synthase 3 and soluble guanylate cyclase on the outcome of cardiac arrest and cardiopulmonary resuscitation in mice (2009), Crit. Care Med., 37, 256-262.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.6.1.2

Cloned(Commentary)

Cloned (Comment) Organism
isozyme sGCalpha1 Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information construction of isozyme sGCalpha1-deficient mice, in contrast to wild-type mice, the neurologic and myocardial functions are reduced in cardiac arrest and cardiopulmonary resuscitation, CPR, the detrimental effects are associated with enhanced inflammation of heart and liver, and increased cell death in heart, liver, and brain, which can be prevented by overexpression of NO synthase 3, overview Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Mus musculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP Mus musculus
-
 3',5'-cyclic GMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 C57BL/6 mice, isozyme sGCalpha1
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
heart
-
 Mus musculus
-
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP
-
 Mus musculus 3',5'-cyclic GMP + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
sGC
-
 Mus musculus
sGCalpha1
-
 Mus musculus
soluble guanylate cyclase
-
 Mus musculus