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Literature summary for 4.6.1.2 extracted from

  • Kumar, P.; Bolden, G.; Arise, K.K.; Krazit, S.T.; Pandey, K.N.
    Regulation of natriuretic peptide receptor-A gene expression and stimulation of its guanylate cyclase activity by transcription factor Ets-1 (2009), Biosci. Rep., 29, 57-70.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
natriuretic peptide the transcription factor Ets-1 regulates the natriuretic peptide receptor-A gene expression and the stimulation of the guanylate cyclase GC-A isozyme Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
Mus musculus 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+
-
Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP Mus musculus
-
3',5'-cyclic GMP + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MA-10 cell
-
Mus musculus
-
mesangial cell
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP
-
Mus musculus 3',5'-cyclic GMP + diphosphate
-
?

Synonyms

Synonyms Comment Organism
GC-A
-
Mus musculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
assay at Mus musculus