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Literature summary for 4.6.1.1 extracted from

  • Defer, N.; Best-Belpomme, M.; Hanoune, J.
    Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase (2000), Am. J. Physiol., 279, F400-F416.
    View publication on PubMed
Search for more literature for 4.6.1.1

Activating Compound

Activating Compound Comment Organism Structure
forskolin
-
 Mus musculus
additional information isoenzyme AC9 is not activated by forskolin Mus musculus

Protein Variants

Protein Variants Comment Organism
Y1082L mutation in AC9 confers both binding and activation by forskolin Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Gallus gallus 16020
-
membrane
-
 Mus musculus 16020
-
membrane
-
 Rattus norvegicus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP Gallus gallus
-
 3',5'-cyclic AMP + diphosphate
-
 ?
ATP Mus musculus
-
 3',5'-cyclic AMP + diphosphate
-
 ?
ATP Rattus norvegicus
-
 3',5'-cyclic AMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
 isoenzyme AC5
-
Mus musculus
-
-
-
Rattus norvegicus
-
 isoenzymes AC6, AC5, AC4, AC 7 and AC 9
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
 Gallus gallus 3',5'-cyclic AMP + diphosphate
-
 ?
ATP
-
 Mus musculus 3',5'-cyclic AMP + diphosphate
-
 ?
ATP
-
 Rattus norvegicus 3',5'-cyclic AMP + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
AC
-
 Gallus gallus
AC
-
 Rattus norvegicus
AC9
-
 Mus musculus
adenylyl cyclase
-
 Gallus gallus
adenylyl cyclase
-
 Mus musculus
adenylyl cyclase
-
 Rattus norvegicus