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Literature summary for 4.4.1.23 extracted from

  • Allen, J.R.; Clark, D.D.; Krum, J.G.; Ensign, S.A.
    A role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylation (1999), Proc. Natl. Acad. Sci. USA, 96, 8432-8437.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.4.1.23

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
epoxypropane + HS-CoM Xanthobacter autotrophicus this enzyme forms component I of a four-component enzyme system, comprising EC 4.2.99.19 2-hydroxypropyl-CoM lyase, component I, EC 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating), component II, EC 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase, component II and EC 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase, component IV that is involved in epoxyalkane carboxylation 2-hydroxypropyl-CoM
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Organism

Organism UniProt Comment Textmining
Xanthobacter autotrophicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
epoxypropane + HS-CoM catalyzes the reaction of CoM with R-epoxypropane at a rate approximately twice of that with S-epoxypropane Xanthobacter autotrophicus 2-hydroxypropyl-CoM
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epoxypropane + HS-CoM this enzyme forms component I of a four-component enzyme system, comprising EC 4.2.99.19 2-hydroxypropyl-CoM lyase, component I, EC 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating), component II, EC 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase, component II and EC 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase, component IV that is involved in epoxyalkane carboxylation Xanthobacter autotrophicus 2-hydroxypropyl-CoM
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 ?

Subunits

Subunits Comment Organism
More this enzyme forms component I of a four-component enzyme system, comprising EC 4.2.99.19 2-hydroxypropyl-CoM lyase, component I, EC 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating), component II, EC 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase, component II and EC 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase, component IV that is involved in epoxyalkane carboxylation Xanthobacter autotrophicus