Application | Comment | Organism |
---|---|---|
medicine | amorpha-4,11-diene is a presursor of artemisinin, artemisinin and derivates are used for the treatment of malaria | Artemisia annua |
Cloned (Comment) | Organism |
---|---|
into the pET30a+ vector for expression in Escherichia coli | Artemisia annua |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | the apparent Km value is 3.4 mmol/l | Artemisia annua |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
69300 | - |
detemined by SDS-PAGE, recombinant protein extended with 17 amino acids after fusion to the His-tag | Artemisia annua |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-trans,6-trans-farnesyl diphosphate | Artemisia annua | - |
amorpha-4,11-diene + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Artemisia annua | - |
- |
- |
Purification (Comment) | Organism |
---|---|
purified by immobilized metal affinity chromatography on a column loaded with Ni2+ | Artemisia annua |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
flower | - |
Artemisia annua | - |
leaf | - |
Artemisia annua | - |
stem | - |
Artemisia annua | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-trans,6-trans-farnesyl diphosphate | - |
Artemisia annua | amorpha-4,11-diene + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADS | - |
Artemisia annua |
ADS1 | - |
Artemisia annua |
amorpha-4,11-diene synthase | - |
Artemisia annua |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
activity assay | Artemisia annua |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
activity assay | Artemisia annua |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 7 | - |
Artemisia annua |