Any feedback?
Literature summary for 4.2.2.20 extracted from
- Therapeutic time window for the application of chondroitinase ABC after spinal cord injury (2008), Exp. Neurol., 210, 331-338.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | rats with a crush in the dorsal funiculi of the C4 segment of the spinal cord are treated with chondroitinase ABC delivered to the lateral ventricle. Treatment is started at the time of injury or after a 2, 4 or 7 days delay. Behavioural testing over 6 weeks shows that acutely treated animals show improve skilled forelimb reaching compared to controls. Chondroitinase-treated animals show greater axon regeneration than controls. The treatment effect on contact placing, stride length and axon regeneration is not dependent on the timing of the start of treatment, but in skilled paw reaching acutely treated animals recover better function | Proteus vulgaris |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Proteus vulgaris | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| chondroitinase ABC | - |
Proteus vulgaris |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
