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Literature summary for 4.2.1.96 extracted from

  • Hauer, C.R.; Rebrin, I.; Thoeny, B.; Neuheiser, F.; Curtius, H.C.; Hunziker, P.; Blau, N.; Ghisla, S.; Heizmann, C.W.
    Phenylalanine hydoxylase-stimulating protein/pterin-4alpha-carbinolamine dehydratase from rat and human liver (1993), J. Biol. Chem., 268, 4828-4831.
    View publication on PubMed
Search for more literature for 4.2.1.96

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-
cytosol
-
 Homo sapiens 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
12000
-
 4 * 12000, SDS-PAGE Homo sapiens
12000
-
 4 * 12000, SDS-PAGE Rattus norvegicus
45000
-
 gel filtration Rattus norvegicus
45000
-
 gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the cytosolic enzyme is involved in the regeneration of tetrahydrobiopterin, the cofactor of aromatic amino acid monooxygenases ?
-
 ?
additional information Rattus norvegicus the cytosolic enzyme is involved in the regeneration of tetrahydrobiopterin, the cofactor of aromatic amino acid monooxygenases ?
-
 ?
additional information Homo sapiens the enzyme is essentially identical to a cofactor that regulates dimerization of a nuclear homeodomain-containing protein involved in transcription ?
-
 ?
additional information Rattus norvegicus the enzyme is essentially identical to a cofactor that regulates dimerization of a nuclear homeodomain-containing protein involved in transcription ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-
liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.2
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the cytosolic enzyme is involved in the regeneration of tetrahydrobiopterin, the cofactor of aromatic amino acid monooxygenases Homo sapiens ?
-
 ?
additional information the cytosolic enzyme is involved in the regeneration of tetrahydrobiopterin, the cofactor of aromatic amino acid monooxygenases Rattus norvegicus ?
-
 ?
additional information the enzyme is essentially identical to a cofactor that regulates dimerization of a nuclear homeodomain-containing protein involved in transcription Homo sapiens ?
-
 ?
additional information the enzyme is essentially identical to a cofactor that regulates dimerization of a nuclear homeodomain-containing protein involved in transcription Rattus norvegicus ?
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 12000, SDS-PAGE Rattus norvegicus
tetramer 4 * 12000, SDS-PAGE Homo sapiens