Any feedback?
Literature summary for 4.2.1.30 extracted from
- Identification and expression of the genes and purification and characterization of the gene products involved in reactivation of coenzyme B12-dependent glycerol dehydratase of Citrobacter freundii (2001), Eur. J. Biochem., 268, 2369-2378.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| DhaF | formerly OrfZ, DhaF-DhaG alpha2beta2 complex rapidly reactivates glycerol-or O2-inactivated hologlycerol dehydratase and activates the enzyme cyanocobalamin complex in the presence of coenzyme B12, ATP and Mg2+ | Citrobacter freundii | |
| DhaG | formerly OrfX, DhaF-DhaG alpha2beta2 complex rapidly reactivates glycerol-or O2-inactivated hologlycerol dehydratase and activates the enzyme cyanocobalamin complex in the presence of coenzyme B12, ATP and Mg2+ | Citrobacter freundii |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| glycerol | suicide inactivation, 65% activity after 3 min, 3% activity after 30 min | Citrobacter freundii |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycerol | Citrobacter freundii | - |
3-hydroxypropanal + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Citrobacter freundii | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycerol | - |
Citrobacter freundii | 3-hydroxypropanal + H2O | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Citrobacter freundii |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
