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Literature summary for 4.2.1.22 extracted from

  • Thorson, M.; Van Wagoner, R.; Harper, M.; Ireland, C.; Majtan, T.; Kraus, J.; Barrios, A.
    Marine natural products as inhibitors of cystathionine beta-synthase activity (2015), Bioorg. Med. Chem. Lett., 25, 1070-1072 .
    View publication on PubMed
Search for more literature for 4.2.1.22

Application

Application Comment Organism
analysis development of 7-azido-4-carbamoylmethylcoumarin as a modified fluorogenic probe for H2S detection with improved solubility in aqueous solutions Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-3-methyl-2-(methylsulfanyl)-3,5-dihydro-4H-imidazol-4-one compound derived from polyandrocarpamines A and B, i.e. 2-aminoimidazolone compounds isolated from the ascidian Polyandrocarpa sp. Homo sapiens
2-methoxy-4-[(Z)-(5-oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenyl acetate compound derived from polyandrocarpamines A and B, i.e. 2-aminoimidazolone compounds isolated from the ascidian Polyandrocarpa sp. Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.083
-
 pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-methoxy-4-[(Z)-(5-oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenyl acetate
0.087
-
 pH not specified in the publication, temperature not specified in the publication Homo sapiens (5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-3-methyl-2-(methylsulfanyl)-3,5-dihydro-4H-imidazol-4-one