Inhibitors | Comment | Organism | Structure |
---|---|---|---|
acetazolamide | - |
Leptonychotes weddellii | |
azide | - |
Leptonychotes weddellii | |
benzolamide | - |
Leptonychotes weddellii | |
bicarbonate | high inhibition | Leptonychotes weddellii | |
brinzolamide | - |
Leptonychotes weddellii | |
bromide | - |
Leptonychotes weddellii | |
Carbonate | high inhibition | Leptonychotes weddellii | |
chloride | - |
Leptonychotes weddellii | |
Cyanate | high inhibition | Leptonychotes weddellii | |
cyanide | high inhibition | Leptonychotes weddellii | |
dichlorophenamide | - |
Leptonychotes weddellii | |
dorzolamide | - |
Leptonychotes weddellii | |
fluoride | - |
Leptonychotes weddellii | |
H2NSO2NH2 | - |
Leptonychotes weddellii | |
H2NSO3H | - |
Leptonychotes weddellii | |
HSO3- | - |
Leptonychotes weddellii | |
hydrochlorothiazide | - |
Leptonychotes weddellii | |
Iodide | - |
Leptonychotes weddellii | |
methazolamide | - |
Leptonychotes weddellii | |
additional information | no inhibition by perchlorate | Leptonychotes weddellii | |
nitrate | - |
Leptonychotes weddellii | |
nitrite | - |
Leptonychotes weddellii | |
PhAsO3H2 | - |
Leptonychotes weddellii | |
PhB(OH)2 | - |
Leptonychotes weddellii | |
saccharin | - |
Leptonychotes weddellii | |
sulfamate | - |
Leptonychotes weddellii | |
sulfamide | high inhibition | Leptonychotes weddellii | |
sulfate | - |
Leptonychotes weddellii | |
Sulfide | - |
Leptonychotes weddellii | |
thiocyanate | high inhibition | Leptonychotes weddellii | |
zonisamide | - |
Leptonychotes weddellii |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | catalytically crucial | Leptonychotes weddellii |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30000 | - |
x * 30000, about, SDS-PAGE | Leptonychotes weddellii |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2CO3 | Leptonychotes weddellii | - |
CO2 + H2O | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leptonychotes weddellii | - |
adult female Weddell seals | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Leptonychotes weddellii | - |
intestine | - |
Leptonychotes weddellii | - |
kidney | - |
Leptonychotes weddellii | - |
liver | - |
Leptonychotes weddellii | - |
lung | - |
Leptonychotes weddellii | - |
spleen | - |
Leptonychotes weddellii | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2CO3 | - |
Leptonychotes weddellii | CO2 + H2O | - |
r |
Subunits | Comment | Organism |
---|---|---|
? | x * 30000, about, SDS-PAGE | Leptonychotes weddellii |
Synonyms | Comment | Organism |
---|---|---|
alpha-carbonic anhydrase | - |
Leptonychotes weddellii |
lwCA | - |
Leptonychotes weddellii |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
20 | - |
assay at | Leptonychotes weddellii |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Leptonychotes weddellii |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.046 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | PhB(OH)2 | |
0.055 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | H2NSO3H | |
0.057 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | PhAsO3H2 | |
0.06 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | Carbonate | |
0.07 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | cyanide | |
0.07 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | H2NSO2NH2 | |
0.087 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | Cyanate | |
0.097 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | thiocyanate | |
0.1 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | bicarbonate | |
0.59 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | HSO3- | |
0.74 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | fluoride | |
0.82 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | sulfate | |
0.83 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | azide | |
0.89 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | chloride | |
0.9 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | nitrite | |
1 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | Sulfide | |
1.01 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | bromide | |
20 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | Iodide | |
55.6 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | nitrate |