Literature summary for 4.1.3.38 extracted from

Basset, G.J.; Ravanel, S.; Quinlivan, E.P.; White, R.; Giovannoni, J.J.; Rebeille, F.; Nichols, B.P.; Shinozaki, K.; Seki, M.; Gregory, J.F., 3rd; Hanson, A.D.
Folate synthesis in plants: the last step of the p-aminobenzoate branch is catalyzed by a plastidial aminodeoxychorismate lyase (2004), Plant J., 40, 453-461.

Cloned(Commentary)

Cloned (Comment)	Organism
cDNAs are shown to encode functional enzymes by complementation of an Escherichia coli pabC mutant, and by demonstrating that the partially purified recombinant proteins convert 4-amino-4-deoxychorismate to 4-aminobenzoate	Solanum lycopersicum
cDNAs are shown to encode functional enzymes by complementation of an Escherichia coli pabC mutant, and by demonstrating that the partially purified recombinant proteins convert 4-amino-4-deoxychorismate to 4-aminobenzoate. The full-length Arabidopsis ADC lyase polypeptide is translocated into isolated pea chloroplasts and, when fused to green fluorescent protein, directed the passenger protein to Arabidopsis chloroplasts in transient expression experiments	Arabidopsis thaliana

Cloned (Comment)

Organism

Solanum lycopersicum

cDNAs are shown to encode functional enzymes by complementation of an Escherichia coli pabC mutant, and by demonstrating that the partially purified recombinant proteins convert 4-amino-4-deoxychorismate to 4-aminobenzoate. The full-length Arabidopsis ADC lyase polypeptide is translocated into isolated pea chloroplasts and, when fused to green fluorescent protein, directed the passenger protein to Arabidopsis chloroplasts in transient expression experiments

Arabidopsis thaliana

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	no feedback inhibition by physiological concentrations of 4-aminobenzoate, its glucose ester, or folates	Arabidopsis thaliana

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
plastid	-	Arabidopsis thaliana	9536	-
plastid	-	Solanum lycopersicum	9536	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4-amino-4-deoxychorismate	Arabidopsis thaliana	last step of the 4-aminobenzoate branch	4-aminobenzoate + pyruvate	-	?
4-amino-4-deoxychorismate	Solanum lycopersicum	last step of the 4-aminobenzoate branch	4-aminobenzoate + pyruvate	-	?

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	-	-	-
Solanum lycopersicum	-	Mill. cv. Micro-Tom	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-amino-4-deoxychorismate	last step of the 4-aminobenzoate branch	Arabidopsis thaliana	4-aminobenzoate + pyruvate	-	?
4-amino-4-deoxychorismate	last step of the 4-aminobenzoate branch	Solanum lycopersicum	4-aminobenzoate + pyruvate	-	?

Synonyms

Synonyms	Comment	Organism
ADC lyase	-	Arabidopsis thaliana
ADC lyase	-	Solanum lycopersicum