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Literature summary for 4.1.1.9 extracted from
- Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells (2008), J. Cell. Physiol., 217, 478-485.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| palmitate | the activity of MCD elicits a dose-dependent increase (between 25% and 60%) in cells exposed to increasing concentrations of palmitate (0.1-0.8 mM) | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| L-6 myoblast cell | - |
Rattus norvegicus | - |
| skeletal muscle | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Malonyl-CoA | - |
Rattus norvegicus | Acetyl-CoA + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MCD | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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