KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.87 | - |
3-methyl-2-oxopentanoate | 25°C, pH 7.2 | Rattus norvegicus | |
2 | - |
2-Oxoisohexanoate | 25°C, pH 7.2 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-methyl-2-oxopentanoate | Rattus norvegicus | - |
CO2 + 2-methylbutanal | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
enzyme may be a component of an enzyme complex named alpha-ketoisocaproate:alpha-keto-beta-methylvalerate dehydrogenase | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxoisohexanoate | 38% of the activity with L-3-methyl-2-oxopentanoate | Rattus norvegicus | CO2 + isopentanal | - |
? | |
3-methyl-2-oxopentanoate | - |
Rattus norvegicus | CO2 + 2-methylbutanal | - |
? | |
L-3-methyl-2-oxopentanoate | - |
Rattus norvegicus | CO2 + 2-methylbutanal | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thiamine diphosphate | stimulates moderately | Rattus norvegicus |