Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + oxaloacetate | Rattus norvegicus | - |
GDP + phosphoenolpyruvate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + oxaloacetate | - |
Rattus norvegicus | GDP + phosphoenolpyruvate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PEPCK-M | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
GTP | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme loss impairs gluconeogenesis from lactate, lowers plasma glucose, insulin, and triglycerides, reduces hepatic glycogen, and increases glycerol turnover | Rattus norvegicus |
metabolism | approximately a third of gluconeogenesis comes from the enzyme | Rattus norvegicus |