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Literature summary for 4.1.1.17 extracted from

  • Govoni, M.; Bonavita, F.; Shantz, L.M.; Guarnieri, C.; Giordano, E.
    Overexpression of ornithine decarboxylase increases myogenic potential of H9c2 rat myoblasts (2010), Amino Acids, 38, 541-547.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
alpha-difluoromethylornithine specific and irreversible ODC inhibitor, complete inhibition at 0.1 mM Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
H9c2 cell
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-ornithine
-
Rattus norvegicus putrescine + CO2
-
?

Synonyms

Synonyms Comment Organism
ODC
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus ODC activity in H9c2 cells increases more than 2fold after 2 h of insulin treatment (200 nM) up