Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.1.17 extracted from

  • Kawano, K.; Masuda, H.; Yano, M.; Kihara, K.; Sugimoto, A.; Azuma, H.
    Altered nitric oxide synthase, arginase and ornithine decarboxylase activities, and polyamine synthesis in response to ischemia of the rabbit detrusor (2006), J. Urol., 176, 387-393.
    View publication on PubMed
Search for more literature for 4.1.1.17

Activating Compound

Activating Compound Comment Organism Structure
additional information ischemia increases ODC activity, overview Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-ornithine Oryctolagus cuniculus altered nitric oxide synthase, arginase and ornithine decarboxylase activities, and polyamine synthesis in response to ischemia of the detrusor in the bladder, ischemia increases ODC activity, overview putrescine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bladder muscularis and mucosa, healthy and ischemic, ischemia increases ODC activity Oryctolagus cuniculus
-
detrusor of healthy and ischemic bladder Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 altered nitric oxide synthase, arginase and ornithine decarboxylase activities, and polyamine synthesis in response to ischemia of the rabbit detrusor, polyamine levels in ischemic detrusor tissue, overview Oryctolagus cuniculus
0.0000011
-
 healthy bladder, mucosa Oryctolagus cuniculus
0.0000039
-
 healthy bladder, muscularis Oryctolagus cuniculus
0.0000132
-
 ischemic bladder, mucosa Oryctolagus cuniculus
0.0000311
-
 ischemic bladder, muscularis Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-ornithine
-
 Oryctolagus cuniculus putrescine + CO2
-
 ?
L-ornithine altered nitric oxide synthase, arginase and ornithine decarboxylase activities, and polyamine synthesis in response to ischemia of the detrusor in the bladder, ischemia increases ODC activity, overview Oryctolagus cuniculus putrescine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
ODC
-
 Oryctolagus cuniculus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Oryctolagus cuniculus