Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dynasore | interferes in vitro with Drp1 (the mitochondrial dynamin) activity of dynamin 2, acts as a potent inhibitor of endocytic pathways known to depend on dynamin by rapidly blocking coated vesicle formation; interferes in vitro with the GTPase activity of dynamin1, acts as a potent inhibitor of endocytic pathways known to depend on dynamin by rapidly blocking coated vesicle formation; interferes in vitro with the GTPase activity of dynamin 2, acts as a potent inhibitor of endocytic pathways known to depend on dynamin by rapidly blocking coated vesicle formation | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | Homo sapiens | - |
GDP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
recombinantly expressed in insect cells | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Drp1 | - |
Homo sapiens |
dynamin 1 | - |
Homo sapiens |
dynamin 2 | - |
Homo sapiens |
mitochondrial dynamin | - |
Homo sapiens |