Literature summary for 3.5.4.12 extracted from

Riva, C.M.; Barra, Y.; Cano, J.P.; Tubiana, N.; Lejeune, C.; Merlin, M.; de Sousa, G.; Carcassonne, Y.; Kreis, W.; Lovecchio, J.; Rottachi, C.; Rustum, Y.M.
Correlation between deoxycytidine kinase and deaminase activities and response to therapy with ARA-C (1990), J. Cell. Pharmacol., 1, 79-85.

No PubMed abstract available

Search for more literature for 3.5.4.12

Inhibitors

Inhibitors	Comment	Organism	Structure
arabinosylcytosine	ara-C, deactivating dCMP deaminase	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
dCMP + H2O	Homo sapiens	-	dUMP + NH3	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	human	-
Homo sapiens	-	patients with acute nonlymphocytic leukemia	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
CCRF-CEM cell	-	Homo sapiens	-
KG-1 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
dCMP + H2O	-	Homo sapiens	dUMP + NH3	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)